Is leg swelling from amlodipine dangerous. Changes in skin color around a varicose vein.
She seemed to be of the point of view that since it is only a side-effect, it does not really matter. Lowering blood pressure can reduce the risk of strokes and heart attacks. Dr. sleepiness. unpleasant breath odor. Some side effects may occur that usually do not need medical attention. vomiting of blood. Sep 1, 2016 · Leg edema is a common adverse effect of dihydropyridine Calcium Channel Blockers (CCB) that may need dose reduction or drug withdrawal, adversely affecting the antihypertensive efficacy. 1 out of 10 from a total of 19 ratings on Drugs. These symptoms are usually constant, but may come and go. blurred or loss of vision. However, some people find its common side effects such as fluid retention (edema), dizziness, flushing, palpitations, fatigue and digestive distress are hard to handle. Incidence not known. Foot, leg, and ankle swelling is common when the person also: Injury or surgery involving the leg, ankle, or foot can also cause swelling. Jul 28, 2023 · Treatment. This can be uncomfortable. severe bleeding*. is a serious side effect of amlodipine. 37% of reviewers reported a positive effect, while 37% reported a negative effect. Oct 31, 2018 · Amlodipine with or without other antihypertensives was used by 498 (96. 35% of reviewers reported a positive effect, while 44% reported a negative effect. Aug 18, 2017 · Dear Dr. ankle and leg swelling *. itching. fever or chills. Silviu Pasniciuc answered. You may need medical attention, especially if you have sudden or worsening water retention. The present cohort study reported by Scott Martin Vouri et al. Diet: Diets high in sodium can cause an overload of the body's filtering mechanisms. Facial flushing, redness. Jun 3, 2024 · double vision. In rare cases, when you first start taking amlodipine or increase your dosage, your chest pain may get worse or you Apr 21, 2024 · Amlodipine, an oral dihydropyridine calcium channel blocker, demonstrates prolonged efficacy by inhibiting voltage-dependent L-type calcium channels. Roach: I am a 77-year-old man in good health. It usually occurs in the lower limbs of the body, and may result from localized problems with blood vessels, side effects of certain medications, or existing underlying conditions that cause disrupted blood flow or excess fluid retention. I have been on this for about 18 months firstly on 5mg then 10. lightheadedness. Skin that holds a dimple, also known as pitting, after it's been pressed for a few seconds. About amlodipine. 3% (249/505), only amlodipine was used as an antihypertensive, while in the remaining, various combinations of agents based on achievement of optimum blood pressure were used. This is a sudden swelling of your face, arms, legs, lips, tongue, throat, or intestines. Feeling sick (nausea), indigestion or heartburn. If you develop swelling with amlodipine, tell your doctor right away because they may be able to change your blood pressure medications slightly to help reduce the swelling. That's why it's important to have regular Oct 11, 2023 · loss of memory. May 12, 2020 · Amlodipine and ankle swelling. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings. This is more common in people who have lung conditions. Is older. There are several alternatives to amlodipine available, including other CCBs, angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), beta blockers, and diuretics. increased sensitivity of the skin to sunlight. Authoring team. May 15, 2024 · Dihydropyridines — The dihydropyridines, including nifedipine, isradipine, felodipine, nicardipine, nisoldipine, lacidipine, amlodipine, and levamlodipine are potent vasodilators that have little or no negative effect upon cardiac contractility or conduction. I have the same symptoms after two weeks on Amlodipine. Some calcium channel blockers also can slow the heart rate. Taking amlodipine with other medicines and herbal supplements. Venous insufficiency occurs when the veins in the lower extremities cannot effectively push blood back to the heart. I have found, after a visit to the GP, that Amlodipine has a common side-effect of causing swelling in the feet. ankle oedema can range from being mild and unnoticed to severely affecting quality of life. Mar 28, 2024 · Side effects include edema in the ankle area, headache, and dizziness. 1. Other side effects not listed may also occur in some patients. This is a life-threatening condition that requires immediate medical . Swelling of your legs and ankles (edema) Dizziness. Jul 13, 2018 · Numb feet and legs too! Im also on amlodipine for high blood pressure and i have been taking it for a week now and started feeling short breath felt like someone was sitting and stabbing me in my heart. Find out how amlodipine treats high blood pressure and helps to prevent heart disease, and how to take it. Amlodipine inhibits the influx of calcium ions across cardiac (heart) and smooth muscle causing relaxation of these muscles and dilation (widening). But oedema can also be a sign of a potentially dangerous condition of pregnancy called pre-eclampsia, where you also have raised blood pressure and protein in your urine. patricia1958. Has veins in the legs that cannot properly pump blood back to the heart (called venous insufficiency, most often due to varicose veins) Injury or surgery involving the leg, ankle, or foot can also cause swelling. Spider veins are like varicose veins, but they're smaller. In order of incidence, the most common side effects of diltiazem are: Swelling of the extremities (peripheral edema) Headache. mild allergic reaction *. joint pain or swelling. pain. Stopping amlodipine could cause hemodynamic changes, rebound high blood pressure, and cardiovascular events. flushing or redness of the skin, especially on the face and neck. This is crazy! If you're taking amlodipine for high blood pressure, you may not have any symptoms. Both angioedema and hives happen when liquid from small blood vessels escapes and fills up Response/effectiveness. Burning, throbbing, muscle cramping and swelling in the lower legs. Interactions. The both felt really heaving and very hot to the touch. Symptoms Apr 17, 2023 · Pedal oedema is a well-known adverse effect of amlodipine, but significantly less frequent if only half of the maximum recommended dosage is used. a recognised adverse effect of the calcium channel blocking agents (CCBs) which may limit their usefulness. Download the leg swelling history taking PDF OSCE checklist, or use our interactive OSCE checklist. Angioedema refers to the localized swelling of the skin. Changes in skin color around a varicose vein. Jun 12, 2024 · Sometimes, swollen legs are a sign of a life-threatening problem that needs urgent evaluation. com/Amlodipine Feb 12, 2020 · Difficulty breathing. fast or irregular heartbeat. sensation of spinning. A wide variety of diagnoses and conditions can cause fluid to build up in your legs. High blood sugar (hyperglycemia). Swelling may also occur after pelvic surgery, especially for cancer. Nifedipine has an average rating of 5. Nov 8, 2019 · A doctor has provided 1 answer. This list may not describe all possible side effects. Amlodipine (Norvasc), beta blockers, clonidine, diltiazem, hydralazine, minoxidil, nifedipine Calf swelling > 3 cm in comparison to contralateral leg + 1: Apr 17, 2022 · pain, tenderness, swelling, redness, or discoloration of the genitals; fever; malaise (feeling generally unwell) Ketoacidosis (high levels of blood acids) in people with type 2 diabetes. Amlodipine may be used to treat heart conditions such as angina and high blood pressure. 5 mg, 5mg, or 10 mg. Move the body as appropriate: Depending on the person, a doctor may recommend movement to help reduce swelling that leads to weeping. May 29, 2023 · Table of Contents. swelling of the ankles, feet, or lower legs. She suggested that it would be a good idea to keep my feet up. Doxazosin has an average rating of 5. Mar 22, 2022 · Angioedema is a reaction to a trigger that causes swelling in the tissue below the inner layer of your skin called the dermis or the layer below a mucous membrane. Medicines that help the body get rid of too much fluid through urine can treat worse forms of edema. Felodipine has an average rating of 5. Bilateral but asymmetric cases can have unilateral causes on each leg of different etiologies or varying degrees, or a unilateral cause superimposed on a background of Jun 20, 2023 · Causes. Jan 3, 2024 · Myxedema affecting the lower legs, known as pretibial edema, is the most common type. Periorbital edema, or edema around the eyes, is also often seen and results in swollen eyelids. Congestive heart failure. And then two days ago both ankles starting swelling up like cancels. abdominal pain. Numbness and tingling of feet, etc. Also you have to keep an eye on your heart rate. Symptoms of peripheral neuropathy. Calcium causes the heart and arteries to squeeze more strongly. 5. If it continues for a long time, the heart and arteries may not function properly. unusual bleeding or bruising. 0 out of 10 from a total of 159 ratings on Drugs. 5 mg of amlodipine a day for high blood pressure. He went back to his doctors after about 3 months May 30, 2024 · Medication: Swelling in one lower leg can be a side effect of many medications that treat common conditions such as high blood pressure, diabetes, and menopause. How and when to take it. muscle pain. Typical : Leg edema or swelling is a typical side effect of calcium channel blockers, such as amlodipine. In typical dosages, amlodipine can cause arterial dilation, says Dr. In this case, you may not feel any different when you take amlodipine. If her amlodipine dose is high (more than 5 mg), she may experience swelling in her legs, ankles, or feet. Brand name: Istin. Some swelling of the feet and ankles occurs in almost half the people who take calcium channel blockers. How it works. Feb 4, 2018 · Swelling for two. Leg swelling isn't always a sign of a heart or circulation problem. Because angiotensin-converting enzyme inhibitors may attenuate ankle swelling by Swelling from amlodipine is a common, but often troublesome side effect of amlodipine with 5% to 9% of people stopping amlodipine because of it. Make sure it is between 60 and 80 while resting. My husband was recently put on it too. burning feeling in the chest or stomach. chest pain. loss in sexual ability, desire, drive, or performance. Swelling in the ankles, feet or legs often goes away on its own. He had swollen ankles, mood swings, bouts of depression, insomnia, pains in his legs etc etc. Posted 9 years ago, 7 users are following. Swollen feet, ankles or fingers. This suggests that an ARB may be an effective alternative for treatment of oedema in patients May 7, 2020 · Fluid retention is one of prednisone’s most famous side effects. Tiredness and sleepiness. The most common ones include: Venous insufficiency. May 8, 2023 · Symptoms of an amlodipine overdose may include fast heartbeat, fainting, and/or redness and warmth in the arms and legs. Your risk for swelling with amlodipine may increase with higher doses of the drug. loss of balance and co-ordination. However, this usually causes swelling in both legs rather than just one. See a GP if it does not get better in a few days. 5 mg of Amlodipine and 40 mg of Telmisartan would provide you very good results. You may report side effects to FDA at 1-800-FDA-1088. Jul 1, 2024 · Check with your doctor immediately if any of the following side effects occur: Less common. Long airplane flights or car rides, as well as standing for long periods of time, often lead to some swelling in the feet and ankles. trouble swallowing. Swelling of the belly, also called the abdomen, so that it's bigger than usual. Diuretics are ineffective. After the first-week period of adjustment, in which it completely knocked me out, I felt normal again and was overjoyed that it lowered and kept my usual 150+/90+ BP down to a textbook Feb 1, 2023 · Causes of Leg Swelling. They are typically used to treat hypertension or chronic stable angina. Other known side effects are: Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Angioedema. High blood pressure adds to the workload of the heart and arteries. Other drugs that may cause peripheral edema include: Other blood pressure medications called beta blockers, clonidine, hydralazine, minoxidil and methyldopa. Rare. passing gas. sexual side effects, such as erectile dysfunction. muscle pain or stiffness. Less common lisinopril side effects include diarrhea, blurred vision, and temporary erectile dysfunction. nausea. muscle weakness, especially in the feet. Restricted range of motion. I take 7. 10 Reported frequency rates for peripheral edema with CCB therapy are quite varied in the literature in part because of the dose‐dependent nature of the phenomenon, and can range from 5% to Jun 5, 2020 · The first thing your doctor may try are diuretics, or water pills. “‘Moon face’ is common, which is swelling in the face that can occur after you’ve been on steroids for a long time,” Dr with the limb passively placed 50 cm below the heart level, and leg weight (Archimedes principle) were measured at baseline, during increasing doses of the dihydropyridine amlodipine (5 and 10 mg UID each for 2 weeks), and after drug withdrawal in 10 hypertensive men. nervousness. feeling of warmth or heat. May 28, 2015 · Amoldipine - dangerous drug - don't take. 3 out of 10 from a total of 817 ratings on Drugs. At 10 mg UID, however, amlodipine blunted postural vasoconstriction and increased Amlodipine has an average rating of 4. Peripheral oedema, including ankle oedema. weakness or heaviness of the legs. headache. Call your doctor for medical advice about side effects. 1 in the December 27, 2019 issue of JAMA Network Open found that a prescribing cascade of a loop diuretic after a dihydropyridine calcium channel bocker (DHCCB) for DHCBB-induced edema was present in 1. ankle oedema can range from being mild Nov 24, 2022 · Lymphedema signs and symptoms include: Swelling of part or all of the arm or leg, including fingers or toes. Feb 26, 2024 · The drug amlodipine is an example. You can have swelling due to fluid buildup from Foot, leg, and ankle swelling is common when the person also: Is overweight. joint pain *. Acute injury. Nov 4, 2022 · The bottom line. burning, stabbing or shooting pain in affected areas. Mild side effects that have been reported with losartan when Swelling may be widespread or confined to a single area. I was on 5mg and trying to wean off of it by taking 2. Feelings of fullness or bloating in the belly. Beta-blockers can cause lung muscle spasms that make it difficult to breathe. People taking it may experience common side effects like dizziness, headache, or a dry cough. A small number of people—less than 2%—may experience muscle pain and muscle cramps as a side effect of amlodipine. Common causes of swollen ankles, feet and legs. irregular breathing. One of the most common of these water pills, also known as diuretics, is furosemide (Lasix). Are dehydrated. dry cough *. Jul 1, 2024 · Nifedipine is a medication used to treat high blood pressure and chest pain. The main symptoms of peripheral neuropathy can include: numbness and tingling in the feet or hands. Sep 26, 2022 · One open-label, blinded end point study found a significant reduction in the incidence of markers of ankle oedema in the group treated with valsartan in addition to amlodipine versus amlodipine alone, along with significantly reduced blood pressure. 5 out of 10 from a total of 66 ratings on Drugs. Has a blood clot in the leg. Wearing compression garments and raising the affected arm or leg higher than the heart helps. Lisinopril works by blocking a substance in the body that causes the blood vessels to tighten. Jul 13, 2022 · Elastic bands in socks or clothes that leave indented lines. Oedema is usually caused by: standing or sitting in the same position for May 21, 2007 · Therefore, a more potent CCB like amlodipine will be associated with higher rates of edema development than a somewhat lower‐potency CCB like diltiazem. Treatment of leg swelling is different for each person and depends on the underlying cause. stomach pain. Has a leg infection. A feeling of heaviness or tightness. Swelling in the ankles, feet and legs is often caused by a build-up of fluid in these areas, called oedema. Apr 27, 2024 · Leg swelling caused by fluid buildup in leg tissues is known as peripheral edema. Talk to your doctor or pharmacist if this advice does not help or the side effects last more than a few days: Oct 31, 2022 · Losartan potassium is a prescription to treat high blood pressure, diabetic nephropathy, and stroke risk. irritability. 8%) patients, while S-amlodipine was used instead of amlodipine in the remaining 16 patients. Other symptoms depend on Swelling can be experienced in your hands or anywhere in the body. Hair loss. Jun 14, 2014 · This can be a dangerous medication - beware! Posted 10 years ago, 64 users are following. Learn more about the possible side effects of nifedipine, how to report them, and when to seek medical attention from Mayo Clinic, a trusted source of health information. dizziness, lightheadedness, or fainting. What might help Feb 3, 2023 · severe dizziness. loss of voice. Blood clots, pregnancy, infections, injuries, medications, heart disease, kidney disease, and liver disease are all common causes of leg swelling. fainting. More about the medication http://pharmacisttips. Aug 3, 2021 · A boxed warning alerts doctors and patients about drug effects that may be dangerous. inability to move the arms, legs, or facial muscles. Beta Oct 12, 2022 · headache. lack of appetite. Apr 1, 2024 · This can damage the blood vessels of the brain, heart, and kidneys resulting in a stroke, heart failure, or kidney failure. thrombotic thrombocytopenic purpura *. Aug 29, 2022 · The most common side effect of oral diltiazem is swelling due to fluid retention (edema), particularly in the hands, feet, and lower legs. It is usually the result of a reaction to certain allergens, such as nuts or specific Jul 28, 2023 · Symptoms of edema include: Swelling or puffiness of the tissue right under the skin, especially in legs or arms. Heart palpitations—rapid, pounding, or irregular heartbeat. Stomach pain. Lisinopril (Zestril) is an angiotensin-converting enzyme (ACE) inhibitor that’s commonly prescribed to treat high blood pressure. Feb 6, 2024 · An achy or heavy feeling in the legs. These side effects may go away during treatment as your body adjusts to the medicine. However, low blood pressure is the most common side effect of a diltiazem injection. Its effectiveness in lowering blood pressure has a few downsides. Jul 1, 2024 · swelling of the eyelids, face, lips, hands, or feet. 27% of reviewers reported a positive effect, while 55% reported a negative effect. Recurring infections. The main causes of widespread swelling are heart, liver, and kidney disorders. yellow eyes or skin. It also can be caused by a problem with the lymphatic system or the kidneys. * To learn more about this Amlodipine is used alone or together with other medicines to treat hypertension (high blood pressure). Feb 1, 2000 · Amlodipine (5 mg UID) increased leg weight without modifying postural vasoconstriction (the percent skin blood flow decrease from horizontal to dependent position), which indicates that extravascular fluid shift was independent of postural skin vasoconstriction. Compression stockings are specifically recommended for managing swollen ankles that result from chronic venous insufficiency , with a compression intensity of 20 to 30 mm Hg for mild swelling Sep 27, 2022 · Leg pain is not commonly associated with amlodipine. uncontrolled movements, especially of the face, neck, and back. severe allergic reaction *. Confusion. thinning of the hair. Since taking the medication, I have developed lower-leg swelling that is annoying. By blocking calcium, calcium channel blockers allow blood vessels to relax and open. Sudden onset of swelling may indicate a serious disorder, so people should see a doctor right away. Taking a comprehensive leg swelling history is an important skill often assessed in OSCEs. redness or other discoloration of the skin. ankle oedema can range from being mild and Stomach pain and nausea. com. This action interrupts initial calcium influx, distinguishing it within its pharmacological class. This guide provides a structured framework for taking a history from a patient with leg swelling in an OSCE setting. Peripheral edema can also be commonly observed in pregnancy. Swelling due to edema will usually make the skin feel tight, heavy, or sore. These problems may affect the legs. If you want to quit taking amlodipine, you must talk to your doctor. Heavy feeling in arms or legs from the extra weight of the water. In 49. particularly in an aging population who are more likely to have co-morbidities. If you're taking amlodipine for angina, it will probably take a couple of weeks before you feel Amlodipine has an average rating of 4. inability to speak. The main causes of swelling of a single limb are blood clots in a vein and an infection. numbness or tingling in the hands, feet, or lips. * For more Feeling weak, sleepy or dizzy. Oct 11, 2023 · loss of memory. More chest pain or a heart attack. Learn about side effects, warnings, dosage, and more. Swelling of the ankles, hands, or feet. Mild edema usually goes away on its own. Urinary tract infection (UTI) or cystitis. Many of the warning signs are similar to some metformin side effects, such as stomach pain Feb 10, 2018 · Leg swelling with Amlodipine is discussed. Are sick with fever, diarrhea, or throwing up. Answers. Hardening and thickening of the skin (fibrosis) Signs and symptoms can range from mild to severe. Pregnancy, breastfeeding and fertility. Side effects. upper right abdominal or stomach pain. Jun 28, 2023 · Elevate affected body parts: If arms or legs are swollen, resting them above heart level can help reduce swelling naturally. Itching around one or more of the veins. Nausea. Oct 5, 2022 · These are just a few of the more common side effects reported by people who took amlodipine in clinical trials: fatigue. Worse pain after sitting or standing for a long time. Headaches. pain, swelling, or redness in the joints. Aug 18, 2023 · Have severe congestive heart failure. Who can and cannot take it. 44% of patients; especially high rates were found with high DHCCB doses, amlodipine use, in males and with the use of fewer Aug 17, 2023 · The most common cause of peripheral edema in patients over 50 yrs of age is venous insufficiency. Lightly massage swollen limbs: For patients whose skin can handle it, a massage can Aug 23, 2023 · Calcium channel blockers are medicines used to lower blood pressure. twisting movements of the body. Amlodipine has been shown to reduce the likelihood of a heart attack or stroke ( Cardiology and Therapy, Dec. These include: blood in urine. More commonly, however, people may notice “heavy legs” due to swelling. Shortness of breath or difficulty breathing. It is related to aging, but many other underlying comorbid conditions like heart failure, renal failure, liver failure, and trauma can affect any age group. risk of developing ankle oedema whilst using CCB therapy appears Mar 17, 2023 · Serious side effects have been reported with Plavix. Mar 14, 2012 · After previous episodes, I have been unable to walk quickly. Ideally 2. Keeping legs elevated during the day and decreasing amount of salt ingested may help mitigate its side effect. Stopping amlodipine Amlodipine. Nov 28, 2023 · Swelling from amlodipine oral tablets typically happens in your arms, feet, hands, or legs. If a blood clot breaks away and travels to your lungs, it is known as a pulmonary embolism. redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid. Angioedema often happens at the same time as hives (urticaria) and for similar reasons. Amlodipine has an average rating of 4. Hormone drugs, including corticosteroids Nov 24, 2020 · Pitting edema occurs when excess fluid in the body causes swelling that indents when pressure is applied. Please see your doctor. They stop calcium from entering the cells of the heart and arteries. Leg edema is reported to occur less often with (S)-amlodipine compared to conventional racemic amlodipine. redness and swelling of the gums. Most of us who've ever had children remember the misery of aching, swollen ankles towards the end of pregnancy. However, it may cause some side effects, such as headache, dizziness, flushing, or swelling. pains in the stomach, side, or abdomen, possibly radiating to the back. Answered 11/8/2019. “Often, using counter pressure Feb 1, 2024 · Pitting edema is most common in the lower body, particularly in the legs, ankles, and feet. Wong, which can lead to swelling in the legs, excess amounts of blood pooling or collecting in the veins, dizziness, headaches, and flushing. It can be caused by a problem with how blood travels through the body. If you notice any other effects, check with your healthcare professional. Stomach pain or back pain. With a half-life of 30 to 50 hours, amlodipine affords the convenience of once-daily dosing, contrasting with shorter-acting alternatives like Lercanidipine and ankle swelling. loss of interest or pleasure. Last edited 12 May 2020. . Colibri. bloody or cloudy urine. muscle pains, stiffness, tension, tightness, or weakness. Her doctor may have prescribed amlodipine in 2. Hot or warm feeling in your face (flushing) There may be other side effects of amlodipine Apr 15, 2022 · It can cause leg pain and swelling. Mar 29, 2022 · One of the most common side effects of amlodipine is edema, or swelling in the hands, legs, or feet. Ankle, knee, or great toe joint pain. 2021 ). 38% of reviewers reported a positive effect, while 34% reported a negative effect. This may not be the best treatment particularly if the swelling is not due to too much volume. In our clinic, we usually see ankle or foot swelling when the treatment is a once-a-day dose of 10 mg Jul 6, 2020 · Unilateral swelling favors primary and secondary causes of venous or lymphatic compromise and bilateral or generalized swelling suggests systemic etiologies as noted in Table 1. You can achieve the best result by combination therapy which allows you to keep it at a minimum dosage. problems with memory. I took 5mg of amlodipine without problems for about a month. I wouldn’t want anyone to experience this: swollen ankles, legs tingling n feeling like I’m carrying weights, non stop hunger, irritable and sleepy during the day, paranoia and heart palpitations …. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke stuffy or runny nose. To cause as few side effects as possible, options for managing are prioritised in this review: Reduce dosage, switch to lercan … Apr 26, 2023 · Wearing compression stockings applies continuous pressure to the legs, which can help improve circulation and decrease fluid accumulation in the ankles. This does not mean that the medicine is not working, so it's important to keep taking it. Specializes in Internal Medicine. unusual tiredness or weakness. Stretched or shiny skin. rx ix tc sy tp lq xh vm ed ur
